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British Fascial Symposium 2018

v40 2019 “Researcher at Ulm University and Airplanes.”

Electronic Writing Campaign 2019 Posted on Sat, November 23, 2019 14:21:28

Electronic letter writing campaign September 30 2019
NO RESPONSE as of posting on UggleBo Blog – November 23, 2019
Rewritten 23 nov 2019 to be more eloquent.
I will send him in Paper writing campaign to follow shortly.

Ralf Vogt MSc, DO – Fascia Research Group at Ulm University
Engineer aircraft and spacecraft techonoliges.
Author: Fascia in the Osteopathic Field, chapter 48 (2017)”

Dear Ralf Vogt,

I have been a massage therapist since 2002.  The explanations of the muscular system do not answer my question as to why one client can turn from prone to supine with ease while another client uses an extreme amount of energy to do the same action.

I was reading “Fascia in the Osteopathic Field 2017” to find you have Chapter 48 “Fascial treatment of the vascular system”.  The book also highlights you are an engineer with aircraft and spacecraft technologies.  This is the reason I am writing to you.  

I am eager for insight, but I do not have a background in science, so forgive the plain language.

I appreciate your time.  I am curious.  If this reaches your curiosity as well, great.  If it does not, please let me know not to bother you again. (altered from original email sent 30-sept-2019).

All my best in your research,
Allissa from Iowa, Living in Sweden

Part 1-
In aircraft engines, baffles are designed to regulate temperature.  The location of these baffles is critical as well as their integrity. Is this assumption correct?  If baffles crack, they could leak. The result, the engine temperature may increase.  As I see it, the integrity of the baffles are essential for proper function and flow (air in the case of an engine).

When I think of air flow, sound comes to mind.  There are acoustic baffles. Wall panels or hanging ceiling panels absorb sound waves so the din of private conversations can stay at a reasonable level. Without these acoustic baffles re-directing sound waves, the environment or echo of a gymnasium or cafeteria would have a high reverberation.

Often when I pick up a book on fascia, histology and pathology are discussed.  But the Integrity of the Fascia seems to be important, especially for those whose who cannot regulate temperature (Raynaud’s Disease, a viral or bacterial infection).  When reverberation occurs due to fascial integrity loss, leaks happen, I believe.   The Ebola virus compromises the interfaces of separating tubes on a macroscale. Fluids flow into areas where they are not supposed to.

Fascia is observed as long continuous tubes. Here lies, a is similarity of a human and a tree. The xylem of a tree, defies gravity as fluid moves upwards due to compressive forces. Alternations between loose and dense connective tissue, may be, a way of fluids to move against gravity. But could the dis-Integrity or fascial membranes be the cause as to why some clients cannot move with ease?  

A leak or crack occurs, and the mechanical stress changes therefore transduction is also altered.  The Somatosensory system, Interoception or Haptics no longer function efficiently.

Most of the time the body works without problems, but the older someone is or after a viral / bacterial infection, the body has trouble recovering (Dysautonomia, POTS Syndrome, ME and CFS). Even a healthy teenager could get a viral infection which causes body wide issues, Ian Waterman for example. He lost his ability to Propriocept after an illness. The common cold virus takes away ones center of gravity and balance. Are these the result of Fascia Dis-Integrity?

Collagen is water repelling, hydrophobic. Hyaluronan is water loving, hydrophillic. In loose connective tissue, the GAGs and PGs are opposites.  

These opposite forces encourage fluid and nutrients to flow despite gravity, as water is a diamagnet, repelling.  When a leak or a crack happens in an engine baffle, the baffle is a material without an electric charge, but in fascia there is a bioelectric potential which changes as well.  

  • Would dis-Integrity cause ……
  • local inflammation?  
  • transduction signaling problems (phototransduction, mechanotransduction of the somasensory system – Poor Introception)?
  • MORE importantly-
  • Would Human Haptics be impeded by this lack of Fascia Integrity?

Part 2-
As an engineer, are there any similarities to passive stabilizers in the human?

After watching the YouTube video of passive roll damping system, FLUME SYSTEM, used by Hoppe-Marine GmbH in Germany, can you tell me if, there is anything like passive stabilizers used in ships to help them balance also used in the human?

I liken this balance phenomena like the Integrity of Fascia = movement in an effortless manner vs DisIntegrity of Fascia = one cannot turn over on my massage table – movement is full of effort. Would you agree or disagree?

FLUME Stabilization System

https://www.youtube.com/watch?v=dtEJamVv05M



v30 2019 “Cancer and Microbes.”

Electronic Writing Campaign 2019 - Fascia Posted on Sat, November 23, 2019 14:00:54

Peter was kind enough to respond to my email within 7 minutes. He apologized for no clear answers to give me. Microbes and the fascia/conduit system to propagate tissue is outside of his area of expertise.

He suggested need for tissue samples and perform 3D microscopy to address questions scientifically.

Original email dated v30 fredag den 26 juli 2019

To: Peter Friedl European Onocology researcher
Re: Cancer “Stop Signals”, perhaps a mycologist could help. Fascia is our Stroma.

Lieve Mijnheer Friedl,
I have read some of your Research Papers with Stephanie Alexander.  Thank you for being in Bruce Schonfeld’s documentary “The Secret Life of Fascia, part 1”.  Sue Hitzmann spoke very highly of your work and lecture at The 5th Fascial Research Congress in Berlin last November.

Dr. Tom Findley spoke in 2015 at the Joint Conference on Acupuncture, Oncology and Fascia.  He said, looking for lost keys under the light will not lead to finding the keys.  We look under the light because we can see better, but the keys are somewhere else.

In the same theme, I am writing to you.  You are the researcher / scientist, I am the curious student of fascia and microbes.  If one wants to find the “Stop Signals”, could you please speak to someone who knows about small communities – such as a mycologist, a biologist specializing in mycology, about the nano-environment?

The Extra Cellular Fluid and Stroma is where microbes live, thrive and communicate.  Perhaps a mycologist from Micropia can shed light where there is darkness on cellular behavior as well as microbial behavior.  

Thank you kindly for reading.
Allissa from Iowa, Living in Sweden

CELL, Volume 147, Issue 5, 23 November 2011, Pages 992-1009
“Cancer Invasion and the Microenvironment: Plasticity and Reciprocity”
Cancer cells recapitulate the types and mechanisms of migration used by normal, nontumor cells. They activate the same machineries for changing shape, generating force, and remodeling ECM (Friedl, 2004) as normal cells, but neoplastic cells lack physiological  ‘‘stop  signals’’  immobilizing and anchoring the cells (Cox et al., 2001), which arguably perpetuates neoplastic cell migration.

https://www.sciencedirect.com/science/article/pii/S0092867411013547

STROMA – thought from Allissa
Humans are advanced organisms of Stroma like the mycelia of a forest.  Sclerotic fungi vs soft fungi is stroma.  Humans are made up of wandering cells, fixed cells, and fibroblastic cells with different tissue types (loose and dense irregular) with fluid and fibers in between.

A mycologist knows about the forest environment where fungi live, why not use their knowledge and apply it to the human body?

The Naked Scientist discussed Schwann cells in interviews with Professor Alison Lloyd who works at the University College London.  Schwann Cells are Neuroglia which are present in the periphery.  Professor Lloyd states peripheral nerve cell damage can be healed by Schwann cells.  The healing brings back sensation and movement.  

Schwann cells are able to migrate out of a severed nerve across a bridge of tissue.  As they travel, they take the axons they are attached to with them.  Like dragging a broken foot to the hospital, one limp at a time.  Schwann cells NEED a track or a bridge of tissue to travel along.  In Professor Lloyds example, a blood vessel is the surface Schwann cells use as a bridge.

The Stroma type in Professor Lloyd’s example is a blood vessel.  Fascia must be another conduit.   Fascia can be the surface Schwann cells use as a Track or a Bridge for healthy stroma or for cancer stroma which thinks it is unhealed.  

Understanding cellular behavior changes as well as microbial behavior comes from bringing other professions into the cancer lab.  Perhaps a mycologist can be the person to shed light on the communication of microbes such as the mycelia of a forest.

Nerve repair provides clue to cancer spread
26 September 2010


It’s this ephrin signalling that tells the Schwann cells to organise themselves into tracks, as directed by the fibroblasts, so the nerves can regrow, a bit like traffic police using special hand signals to direct cars into different queues on a road.
And, importantly, the scientists found that switching off ephrin signalling meant that Schwann cells couldn’t repair nerve damage, proving that it’s a fundamental part of the process. So these findings tell us something important about nerve repair, which will be useful for researchers working on techniques such as nerve grafts, which could repair damaged nerves after accidents or surgery.
So how is this linked to cancer?
Professor Lloyd thinks that cancer cells may be acting a bit like an unhealed wound, hijacking the signals that normally repair nerves.

http:// https://www.thenakedscientists.com/articles/science-news/nerve-repair-provides-clue-cancer-spread

Scientists re-grow damaged nerves 
17 August 2015


Professor Alison Lloyd – “And so, I think what our work suggests is that what you want to do is to mimic the real bridge. So, you want to maybe make tubes with blood vessels, either blood vessels themselves or surfaces that mimic what it is about blood vessels that provide a surface for the Schwann cells. But I think it has broader implications for other diseases as well. The way that certain cancers spread within the body, these cells are moving along the surface of other cells. It has been observed that cells such as melanomas and gliomas for example.”

https://www.thenakedscientists.com/articles/interviews/scientists-re-grow-damaged-nerves

“They’re brain tumours and they’re very, very invasive. That’s the major problem with them but they also seem to be migrating along the surface of blood vessels. So, it’s possible that when these cancer cells are moving and they’re moving along blood vessels, they’re using the same mechanisms that you see following an injury and they’re co-opting this type of behaviour in order to spread. And so again, if we can understand that better then possibly, we can understand better how tumours spread and then maybe do something about it.”

https://www.thenakedscientists.com/articles/interviews/scientists-re-grow-damaged-nerves

Panel Discussion, OSHER Joint Conference – November 2015
OSHER Center for Integrative Medicine

https://www.youtube.com/watch?v=_hHUjmHXIi8
@36:00 – 37:10 – Dr. Tom Findley
Professor of Physical Medicine and Rehabilitation, Rutgers, New Jersey Medical School, VA New Jersey Health Care System

“Looking for keys under the light….…muscle does not get cancer metastasis very much. So why is it so resistant? Muscle actually makes a small molecular product that you can filter out of a muscle cell culture which will kill tumor cells – so activating muscle may have protective effects elsewhere in the body not just on muscle….”

http:// https://www.youtube.com/watch?v=_hHUjmHXIi8



v28 2019 “Immunologist meet Chef.”

Electronic Writing Campaign 2019 Posted on Sat, November 23, 2019 13:48:49

Electronic letter writing campaign July 14 2019

Jeppe Madura Larsen, Researcher Denmark’s Technical Institute – Research group for Food Allergy

David Zilber is Director of Fermentation at Noma. Author: The Noma Guide to Fermentation

Dear Mr Larsen from Denmark meet David Zilber from Denmark (1).
I am writing to you based on research and questions into pain, Parkinson’s, and dysbiosis.  I wrote to David Zilber on Facebook as well about you. I believe you two together could do good things together. 

David Zilber has a gift that I think could transform medicine.  Next to David Bouley, Mr Zilber is a young equal. 

Scientists are finding low levels of Prevotella copri in fibromyalgia sufferers (2) also research from Helsinki has shown Parkinsons Patients have lower Prevotella family in their gut microbiome (3). 

Strangely, your Immunology Paper 2017 finds Prevotella can be inflammatory and bad – yet at the same time- good for the lungs of asthma and COPD sufferers. “The immune response to Prevotella bacteria in chronic inflammatory disease”

As if Prevotella has a MultiplePersonality Disorder. I find this multiple personality…… odd. Don’t you?

Sarkis Mazmanian has indicated Short Chain Fatty Acids can be anti-inflammatory in the gut, yet pro-inflammatory in the brain (4). In May 2019, his lab at Caltech produced research linking the gut microbiome of humans with Autistic-like behavior in mice. (5)

How is this possible?  

Would you consider crossing the border of medical science with the culinary arts? Would you collaborate with a chef?

Is it possible these microbes need to be in teams or pairs in order to be commensal instead of pathobionts?

Food is our medicine.  Food can be paired up; therefore, protective. Unlike pharmaceuticals which target specific receptors, food has a multitude action plans.

Thank you for reading,
Allissa Harter from Iowa, Living in 🇸🇪 Sweden 

Resources:
David Zilber on Science Friday – July 12, 2019
“World-Class Tips For The Home Fermenter”

The following is an excerpt of The Noma Guide to Fermentation by René Redzepi and David Zilber.

“There are thousands of products of fermentation, from beer and wine to cheese to kimchi to soy sauce. They’re all dramatically different creations, of course, but they’re unified by the same basic process. Microbes—bacteria, molds, yeasts, or a combination thereof—break down or convert the molecules in food, producing new flavors as a result. Take lacto-fermented pickles, for instance, where bacteria consume sugar and generate lactic acid, souring the vegetables and the brine in which they sit, simultaneously preserving them and rendering them more delicious. Cascades of secondary reactions contribute layers of flavors and aromas that didn’t exist in the original, unfermented product. The best ferments still retain much of their original character, whether that’s a touch of residual sweetness in a carrot vinegar or the floral perfume of wild roses in a rose kombucha, while simultaneously being transformed into something entirely new.”

https://www.sciencefriday.com/segments/world-class-tips-for-the-home-fermenter/

2) “First Evidence’ Links Gut Bacteria, Fibromyalgia”. 
The findings were published online June 18 2019 in the Journal Pain

3) Parkinson’s research – University of Helsinki – Filip Scheperjans MD, PhD and Velma T.E.Aho MSc, BA

4) “Proving causality in the gut brain axis”-  by Sarkis Mazmanian, Caltech

https://m.youtube.com/watch?v=owj2gkomv2s

5) Sarkis Mazmanian Lab
ARTICLE VOLUME 177, ISSUE 6, P1600-1618.E17
MAY 30, 2019
“Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice”

https://www.cell.com/cell/fulltext/S0092-8674(19)30502-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867419305021%3Fshowall%3Dtrue

Article about study: Now researchers show the collection of bacteria and other microorganisms in the gut known as the microbiome contributes to autism-like behaviors such as decreased social interactions and repetitive actions in mice. The discovery means that new therapies for autism based on the microbiome might be possible.

“While all studies in mice need to be validated in humans, our discoveries suggest that microbiome-based treatments may be effective in ASD,” said Sarkis Mazmanian, a microbiologist at CalTech who led the new research.